A Rare Lifestyle Estate on 3.57 All-Usable Acres in Artesian Privately gated at the end of a long, tree-lined drive, 16733 Calle Hermosa presents a remarkable opportunity to own a fully usable estate compound designed for refined living and long-term flexibility. Set amid mature citrus groves and expansive, level grounds, this turnkey property blends timeless architecture with resort-inspired amenities and future expansion potential - all within the prestigious Artesian enclave of North County San Diego. Built in 2008 and impeccably maintained, the 5,545-square-foot main residence showcases warmth and craftsmanship through soaring ceilings, oak wood floors, and abundant natural light. A dramatic great room with two-story windows, exposed beams, and multiple French doors creates a seamless indoor-outdoor connection to the covered loggia and sparkling pool beyond - an ideal setting for both intimate gatherings and grand entertaining. The chef's kitchen is thoughtfully appointed with a 70" Frigidaire Professional refrigerator, Dacor six-burner range, double ovens, dual Fisher & Paykel dishwasher drawers, walk-in pantry, and inviting breakfast nook, while the main-level primary suite offers a serene retreat with spa-like bath and garden views. Complementing the main residence is a 918-square-foot detached guest house featuring a full kitchen, living room, bedroom, and bath - ideal for multigenerational living, visiting guests, or income potential. A separate 529-square-foot pool house with bonus garage space below provides additional flexibility for a wellness studio, creative workspace, gym, or collector's storage, transforming the property into a true private lifestyle compound. Outdoor living unfolds across Cantera stone patios, lush lawns, and resort-style amenities including a pool, spa, covered dining areas, and mature landscaping that enhances both privacy and beauty. The 3.57 all-usable acres offer rare versatility, with ample space to envision a pickleball court, vineyard, equestrian facilities, or additional garages - inviting future customization while remaining completely turnkey today. Zoned for the San Dieguito School District and ideally positioned near coastal destinations, top schools, and major conveniences, this extraordinary offering represents a compelling blend of privacy, flexibility, and enduring value within Artesian Estates - a setting where timeless design meets limitless possibility.